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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f957010cdd4dba012f5c71546a45a710862fe527942531816fb0a96f5f6a2be3' 
  AND token = '2UzzMIVn9s+XOtpeSQrN/tvaZe7j+egNsJR9pig8ZAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}