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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7b7f193c3b658a3f15b4ba371bfbba2d5d5a22be6563466d193baa59f2e856' 
  AND token = 'T/PB0teGoMyxEEMi4LOvM9/YDwNePRPet/SDJntDaNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}