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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bd1d8d6736854faa1f860da8e8553317e9b3f81bc1bed8db1d482381e4fc04a' 
  AND token = 'PH8NHICqq7Wun5486TUOfPUK+aAQvgz3TxlsB0tXf8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}