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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f838346ba6da6504ac8f0e303a41dd56130bd66468841dff361eec7cde365c92' 
  AND token = 'K8Q/NEHys/JugI4QqN5oWw6NpGLKUJuxRXT3VjgANJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}