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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4678d252d086cb829780b6b3f33fbea378dfb0549bcb8082d8085ed3a4abf07' 
  AND token = 'sF+VxRYWOFvzG6JuC5k1iaQ8+IYU+fFFQhStNDjefMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}