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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7358c19d07edc748a998fe2ef7b4f5695709ce21fc367f4f8f80644c3480aa' 
  AND token = 'eaIP/vTw6bhh2JYke3LG69MnJsfBCfJWgyPoljMIMmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}