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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278092ebc0530830c467157543b532b36cfc0ae424f95c6864b5a7a2e5a876d5' 
  AND token = 'pVck4W/DAU4VF7g/SbYRDryMVC2an7ojkLSoGLvpnHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}