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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fa8ebbbe0f262c0b3604b93ddc4607d5db22cfcabe75e65b28735c55c211920' 
  AND token = 'k7L6ykJZo2IlWUUJmKS0UnoGYG5O+XjFcpvwCih9Jeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}