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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04f1b37801a99d468efd0173012658b8078d1a441a6d9fe14beb4ea27ba24320' 
  AND token = 'x2wOlxbNd0BBJ54G+ov72KdXZqf0+qwKPmgEhwrhySA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}