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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed75c3bb661f048a4e01ae5cb83c08e85b748ea99043a7d1e6abb7e189aed02' 
  AND token = '7MLCwgTnXf+YnDkggDi/wBDAgiM23T1twAyP7NeobHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}