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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390520c6f780a7b6fce82aa23c3391b3dd0c3b75991733a3953a77a6df147b4d' 
  AND token = '8Jdb2J9EaXyxMEhSRzAk1NLea5ChMjplVoykBBzqVfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}