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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f3db8c96e24eafd52c53fd0019ebf0f653eeabeb495525240a0b5a0764bb081' 
  AND token = 'TS5QzTEKkBtOGu8Lwt0TWg9XZ9VDHIesXo4xzUMBu2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}