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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae1f2333f68d439eba6c001a64ec8896f3e7e3c5751852788bfc50bf2b778357' 
  AND token = 'E1r0zXN4PdIflyU59p0yI34ItYZN2NBCIWtGJIFhXCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}