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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ec1fc39d884c0490953625e1b9cc63f2bb0eacd362c7a9be190b830df659f9' 
  AND token = 'lcDqr+aGX4bTxOSQcIMkLa6/lPkxZIDh/U8LXBwd2dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}