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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2adfed19531daa4cecca1dde0b1a4f5ca2fb1f4aa9b101f2cfceaf10132e3218' 
  AND token = 'dyyuMrCt6Zv6y4SMW8m6lFx4O8nA0D9eof3mdBDug48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}