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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ccf603d35774c10f5770431362166370166ed139e399106a64a244641c72399' 
  AND token = 'Wg1yOB1r83q0F0n4NIWjvq9+hR4C/2qA1aLdUXk0ra0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}