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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '501f7e1fa0b6ce0ed375dd0d5bba2c5d6716956860b12d4bf12fb835d81876b2' 
  AND token = '0EdhzB3GsLjTLtruZIywhYCAUXg65hSKLw6CmCfFaoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}