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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd11dedd0f83e22e840d639e20fd8491972ec22085b8afdbd34224e54e65972a4' 
  AND token = 'ZM0Uju/XQboZ7wsoVBS/OS6vNJXiwyF12ByHYKnDoBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}