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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f149c5bfe008cfad448983e380a457e1a8be4d3f8396c9493824c66ddeba458' 
  AND token = 'sdO1wBKJg5ONm+f2KIUlFiEI89mjzS2IMfCV+iVGI4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}