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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335e7695b09fa5a765e282da898d7d3b3f69a56d60de55d120ac0a92fded8e4f' 
  AND token = 'BL3IsR9lDfI3Gya6Vqj9t/mQ+WK8pgI4OflHOIkIHms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}