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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de57c794e622000d4c4b8ce15b1e7724e4d8fc511f22ac1ed97d161596e74576' 
  AND token = 'TqsnkS2OUbq/4p088mhIBdH9a6HJGAWxrRaljZuqkMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}