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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22761b32d0c01b375fa389f31880190b2bd2bd4da98f8e576ee905d39878206c' 
  AND token = '0C0jndxvpKxbo2tDCLtZG9UPT1N9E9RuvxWCi+IzuBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}