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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2702afccefcb7b9834b1680700c9bb5b4b84c1d0ee4d5d70b53248ddeab79c' 
  AND token = 'kxCs38IskT1xLslj+f6oSIeYYn8Ex35y7AjfmXYTewA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}