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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168a28566ab5a4a03a8fc6a88c40b0ac6181a3a6f550882c35701299a58aa095' 
  AND token = 'F3PBkv05AJCNbZxLlGhJaNnYW/djsUE2jY8nCOR8COI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}