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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abf39afde2354398f693718a830edb6a2462aac1fbfcb897e3181652abe85549' 
  AND token = '+dYysLysGrNilMcTENJASiBqx142qGPoes5l0bSgAuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}