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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f743556e283448214f4c59397e0938d2aadad7507df83de0cb46dad26d2ab222' 
  AND token = 'D/eL+4Bk3vh7AP5Ak0W3yo8pUCh3zyZ3DyOL5inOfas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}