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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6741c84ab5bff150c5b17650a22f25d908319e41ba04b270a443324f43a45d44' 
  AND token = 'x4fpUQsvs/g3pGlAa6XhNRPHOiPy5zkTTw5v7h73aHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}