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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e427764e1863cba686b4d83247cfa72d6c8df5283bf1a265c511b6dcb52fcf' 
  AND token = 'NBWupEjkIE9SnqR+AHwyrlMr1f4sjjjX+lN7Yfs46Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}