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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e93847e398ffd81e491303c20b570a12c00eefdd2cb462b2ed99c9a04c018def' 
  AND token = 'co2YENQchObBLaX6/HKLSP7hrIeDI7B3sOgXxmPhOqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}