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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fab2bb18f3b7896b45bd12a2a5aeab5bbed94763c5cea0a28b2575a2048dc4a' 
  AND token = 'LWXYaG0tbWQSu6qmsIXasV1N5RnrzUSo9eY1xUQl55A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}