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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95d5eb3673d27a94075d24225e5ed3210675347e53e467fd45c597d35a112c1a' 
  AND token = 'Z0YlxeMTcAY+3HsvHQnSCp4HljFlPjQJbOBrZ18Deow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}