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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7b8ed25c8bc3d5a92ef6876405866120ee6257bd033407d8d9742cd9ff906ef' 
  AND token = '2NO1+tDNe7ImHNSO4WS35565flOItEo6y9wOIDa3qQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}