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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b2594ad83e6b8bc5471c9a6f22414d9274a9eff477c9750864246dfcd1d7e67' 
  AND token = 'UOEsoJnxzysHBCxY2N3m2+9Y7Q1FXYZ4XvAerTLKTWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}