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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3721caf44c0c87fe3002df8583847f01d4c81631b0d5c3914982872851a744d6' 
  AND token = 'xDMEUJ6633XcccFSHHOZeP/xxGbY24fQritkLexBUtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}