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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9efe8eec7bb761430d4feefc43223d07f58792711fe0f9e8278e6864fe92c2e0' 
  AND token = 'OG0ybuBXnwF+/gu76kCTQqsk5pyE1DrNwrR9m52Rwnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}