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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301b7bc993a5497a291b007930b967ea7d098a343e7a378a3012663022a86dd7' 
  AND token = 'DCLZ0Dd5dCN3ity5hby0xl8yRhpyrnYv34rNAxx0tSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}