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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a444756c2254063a94f7937690b83282bc58bd099cd3d63fa6d06e7b8446ec0d' 
  AND token = 'tIElGr25aVtzC/GagTKoNLIE9VbCQ1Lh6Y+7MDFy5Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00142

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}