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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dea262b993b2e5a2ee63ea99b367417331aae9c15bd45be7a85a89eb78dbf11d' 
  AND token = 'ssFhtEPXXlZUUYRAMkeSGrVD7lOcS0aKe3+ITRZByKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}