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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1c7ef017818347d992f2f837a7c5288f1712abd8d53ecc0d43f87cbb46c404' 
  AND token = 'mxA/KO6y6B40uAIwodQF2JWDRnFr9pLJ0rxMBbEsVmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}