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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eecda43fe6a3b362e9c6b494120cae9abd8068ce2fc37be21bdd37e4b348013' 
  AND token = 'U2LmSL26SPJ8zPRg8WKaA02WVDQBqvOtJuRyvKe4Iwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}