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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a4b27968144fb8f4a572299bf4f53df24e95e6d4bdfbd689fe22a61024330d3' 
  AND token = '2RIny5goBesfQk0iKXa2FypIjgYUAxJbiI4XqeJJcqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}