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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9fed27e5c84e81c1983f72bdb0570ddd8de2f89cc01e6e26be774e75d644e5f' 
  AND token = 'zjBQQfT9s921aRdztD4HEKLNj+/ru5E0/oGAoht8s9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}