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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e888984821d25326686f1691009354dfc7c1805ebfd8a4b79f17d1b1d1cd0afc' 
  AND token = 'l5B1g1GBHI7t2dhcRUPmbP/H6EzhSJ/mZadnLGzz1ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}