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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81839ab348ca69967ddd0c71b28bdd4883630d93dc562cf13bde5dd98c4b384' 
  AND token = 'alF2Id4Ajo/fZvgVIXjlweGkZnguaf+qTa0sEt/V+eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}