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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9c46ab25ee3cf566ae5a41dc2cc0004a75ebabb122071cb464a94de47c3ed0' 
  AND token = 'awMAwBqnuzTO0PytafEAnwASm7tnab83aHK/LqjOcdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}