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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edcd4d61b028d911b52b82a31744c4ccb9262ed869ac22e74de4e581f8dcb6d7' 
  AND token = '5k2zcVJdkaDwOMgVkS07sKwMRAe3T8WKzJe9gh+RXYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}