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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1da1821827f1296763582a7155f246ce19f1abfd4009fd8c032acfb63c10e9df' 
  AND token = 'kowWO0iAp81ea6Eabg2jneqA5qOLvTH2Tn4HtMpziag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}