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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d4d8b6f0aac6321918e262efa276a4158a5b9fd086e484286f085911d08200' 
  AND token = '6z7Wymq5KCfTyFVgJjcFZzp64tle5mMn7+iR+GjmGbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}