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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4002e35a0d30df079a7a4c4bc27daa8e466e5a93d74fd713887714ee3afad92' 
  AND token = '+yQZigOlRoYxb7Jw6KWy3MbHGtCnJ0yPZ46fXhFYMUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}