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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59cbeb853f0e139f801589f74e82d015d94ce44437f80fb5eadd6652720d5f90' 
  AND token = '/AlL6v0WxRz+7ksNP/SoGyr52joxgMVfPy8QUMaK8Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}